Introduction > Main Features of WinEDR
WinEDR is a data acquisition and analysis program for handling signals from electrophysiological experiments. These may include whole-cell patch clamp experiments, single- and two-microelectrode voltage-clamp studies, or simple membrane potential recordings. Whole-cell signals are produced by the summation of currents through the (usually) large population of ion channels in the cell membrane, and thus consist of relatively smooth current or potential waveforms. The amplitude and time course of such signals contain information concerning the kinetic behaviour of the underlying ion channels, and other cellular processes, which can be extracted by the application of a variety of waveform analysis techniques.
WinEDR provides, in a single program, the data acquisition and experimental stimulus generation features necessary to make a digital recording of the electrophysiological signals, and a range of waveform analysis procedures commonly applied to such signals. WinEDR acts like a multi-channel digital tape recorder, collecting series of signals and storing them in a data file on magnetic disk. Its major features are
Recording
· 1-16 analogue input channels.
· Continuous sampling-to-disc at rates up to 100 kHz.
· Stimulus generator.
· Real-time event event frequency, resistance, capacity and fluorescence ratio measurement.
Analysis
· Single-channel transition detection and amplitude/dwell time analysis.
· Event detection and frequency analysis
· Noise analysis
· Miniature synaptic current, ion channel current fluctuation and single-channel current simulations.