FAQ Using - Can I run MyDefrag outside Windows?
MyDefrag is based on the Windows defragmentation library, so Windows must be started. MyDefrag can be run from a bootable Windows CD-rom such as WinPE, Bart's Preinstalled Environment (BartPE), or Ultimate Boot CD for Windows, but cannot be run from a DOS bootable floppy or from Linux.
Tip: Boot into Windows safe mode by pressing F8 when booting, and then run MyDefrag.
It will be slower (the Windows disk cache is off in safe mode), but you can defragment more
files.
Warning: Do not hibernate your computer, then boot with something else (such as BartPE),
and then change the hibernated disk in any way. This will corrupt the disk, a known
hibernation problem. MyDefrag contains a test and will refuse to process hibernated disks.