Offer to purge old quarantined items (Spybot - Search & Destroy 2)

Items are stored in Quarantine in case you might need to restore them at a later stage. If the removal of a file to Quarantine has not effected the functioning of the system there is no need to keep it. When opening the Quarantine, it therefore offers to permanently delete any files older than 90 days.

How often have you used your computer in the past three months? If it has been more than once a week and you have not had any issues since Spybot fixed the problems you should accept this offer.