4.4.2 Changing the action of the Home and End keys
The Unix terminal emulator rxvt disagrees with the rest of the world about what character sequences should be sent to the server by the Home and End keys.
xterm, and other terminals, send ESC [1~ for the Home key, and ESC [4~ for the End key. rxvt sends ESC [H for the Home key and ESC [Ow for the End key.
If you find an application on which the Home and End keys aren't working, you could try switching this option to see if it helps.