4.13.2 ‘Disable Nagle's algorithm’
Nagle's algorithm is a detail of TCP/IP implementations that tries to minimise the number of small data packets sent down a network connection. With Nagle's algorithm enabled, PuTTY's bandwidth usage will be slightly more efficient; with it disabled, you may find you get a faster response to your keystrokes when connecting to some types of server.
The Nagle algorithm is disabled by default for interactive connections.